Unity of Extremes and Ruler's Globus improve hero health and physical attack. They are complex items, so sometimes, their crafting may be confusing. Here is a guide that may help clarify the matter.
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To craft a Ruler's Globus, you need two Alucard's Amulets and a Ruler's Globus Recipe:
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To craft a Unity of Extremes, you need one Alucard's Amulet, one Ruler's Globus (i.e., two Alucard's Amulets and a Ruler's Globus Recipe), and a Unity of Extremes Recipe:
Note
Several heroes need these items for upgrading. Be careful when equipping an item and double-check if you are upgrading the desired hero.